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  • Home
  • Patient Portals
    • EVEXIAS Portal
    • CWI Patient Portal
  • About Me
  • Hormone Therapy
  • Services
    • 1228 Protocol®
    • AdvaTX Laser
    • AGEjet
    • Aquafirme Facial
    • Fillers
    • Micro-Needling
    • Neurotoxins (TOX)
    • PDO Threads
    • Skin Rejuvenation
    • Upneeq (Eye Lift)
    • VI Chemical Peel
    • Platelet-Rich-Fibrin-PRF
    • Sclerotherapy
    • Ultimate Contour
  • Weight Loss
    • Liquid Lipo
    • NAD+
    • Metabolic Weight Loss
    • Membership Options
    • Supplements
    • THINNR
  • Hair Loss
    • What is Hair Loss?
    • DE|RIVE
    • NUTRAFOL
    • Hair - Before & After
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NAD+

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme found in every cell of the body. It plays a key role in cellular repair, energy production, metabolism, and aging processes. 

Benefits of NAD+ Therapy

  • Supports cellular health and longevity
  • Boosts energy and reduces fatigue
  • Enhances cognitive function
  • Reduces inflammation
  • Aids in weight management
  • Supports detoxification and recovery
  • Slows Aging 

Understanding SQ vs. IM NAD+ Injections:

SQ (Subcutaneous) 

Injected just under the skin (fat layer)

Absorb slowly over time

May cause more noticeable side effects ("NAD rush") due to slower diffusion

Best kept at or below 50 mg per injection to minimize discomfort


IM (Intramuscular) 

Injected deep into muscle tissue (upper arm or glute)

Absorbs more quickly and may be better tolerated

Allows for higher dosing per injection (100–600 mg/week common in anti-ging protocols)

Requires more training for home use but can be more comfortable overall 

Why Does SQ Feel More Intense?

SQ injections are absorbed more slowly, which can lead to temporary and more pronounced symptoms such as:


Flushing or itching

Nausea

Dizziness

"NAD rush” a temporary feeling of pressure or anxiety


These symptoms are NOT allergic reactions-just commons side effects of NAD+’s action on cellular receptors and blood vessels. 

How to Minimize the Rush or Discomfort

Start with a low dose (25-50mg) SQ

Inject slowly (over 1–2 minutes)

Take NAD+ earlier in the day to avoid sleep issues

Stay well hydrated before and after

Lie down until symptoms pass 

Instructions & Safety

Injection Site: Abdomen or outer thigh (rotate sites each time)

Injection Volume: Inject slowly

Hydrate well before and after each injection

Store in refrigerator 

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The Cosmetic & Wellness Institute

7810 Ballantyne Commons Parkway, Suite 201, Charlotte, North Carolina 28277, United States

704-559-9313

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